ABSTRACT
Objectives: The prognostic nutrition index (PNI), as an indicator of inflammation and immunity, is calculated by "serum albumin (g/L)+5xlymphocyte count (109/L)."A lower PNI could determine a poor prognosis. Recent publications showed that lower albumin levels are correlated with an increased mortality to the coronavirus disease 2019 (COVID-19). This research aimed to determine the PNIs predictive value of mortality at intensive care units (ICUs) in patients with COVID-19. Method(s): In this retrospective one-centered research, 391 patients with COVID-19 followed up at ICU included in the study. Demographic data, comorbidities, thorax computed tomography, polymerase chain reaction results, length of stay, and laboratory results were collected and statistically analyzed. Result(s): Data from 306 patients were analyzed. Older age (>65-yearsold), hypertension, and cardiac diseases were found to be risk factors. Higher Acute Physiologic Assessment and Chronic Health Evaluation II scores were associated with increased mortality. Increased procalcitonin, creatinine, aspartate aminotransferases, lactate dehydrogenases, white blood cell count, D-dimer, fibrinogen, ferritin, brain-natriuretic peptide, and calcitonin-related peptide were related to mortality. Lower PNI scores were noted as indicators of mortality and prognosis. Conclusion(s): Lower PNI scores indicate increased mortality and the length of stay in patients in the ICU. PNI scores could be useful in predicting the prognosis of patients with COVID-19.Copyright © 2022 by The Cardiovascular Thoracic Anaesthesia and Intensive Care.